Cryocooler for Cryopreservation:
Our BIOSAFE® liquid nitrogen freezer

The BIOSAFE® Cryocooler from Cryotherm has long been a byword for quality and safety. Experience, technology and our know-how make your decision for the cryocooler BIOSAFE® easy. With various sizes and designs of BIOSAFE®, CRYOTHERM offers the complete solution for all cryopreservation tasks.

Substance
Temperature
Scope of application
BIOSAFE® - Cryopreservation at its best with our Cryocooler BIOSAFE®
BIOSAFE® - Cryopreservation at its best with our Cryocooler BIOSAFE®
BIOSAFE® - Cryopreservation at its best with our Cryocooler BIOSAFE®
Service from the planning stage
until commissioning.
Minimal consumption.
Maximum volume.
Simple monitoring
with BIOSAFE® smart
Biobanking 4.0
By SMS or e-mail.
From tiny to gigantic.
Variable volumes.

Standard equipment —
BIOSAFE®

Cryopreservation of cryogenic liquefied nitrogen is proven practice in science, research, medicine, environmental research and technology. The safe cold down to -190 °C in the gas phase and the inert atmosphere enable optimum freezing and storage of valuable medical and biological samples and materials.

With different sizes and designs of BIOSAFE®, supplemented by a wide range of accessories, CRYOTHERM offers the complete solution for your cryopreservation tasks:

  • controlled and programmed freezing of your samples in freezers
  • Administration and backup of your sample data by the sample management system
  • supply system for the cryogenic liquefied nitrogen via APOLLO®-supply tanks, optimised to your requirements
  • or directly supplied from a super insulated transfer line
  • the orderly, safe packaging and classification of the samples using the BIOSAFE® classification system
  • Remote monitoring of your samples by the remote monitoring system CRYO-MESSENGER®

*applies to BIOSAFE® 220/420

Service

Unverwechselbar & ausgefeilt*:
Ergonomischer Hub-/Schwenkmechanismus/ Niedrige, bedienerfreundliche Behälterhöhe.

Doppelt gesichert!
Mechanisch und optional elektronisch verriegelbarer Deckel.

En détail durchdacht:
Hohe Stickstoffreserve unter dem Stellboden reicht je nach Behältergröße für mehrere Tage.

Hohe Lagerkapazität
Für bis zu 23.100 Proben 2ml Ampullen.

Perfekt zu desinfizieren
glatte Oberflächen - auch am Deckel

Niedrige Verdampfungsraten
maximal 2,3%/Tag, gemessen bei Gasphasenlagerung

Optimierte Lagerkapazität
durch Einsatz von platzsparenden High-Efficiency-Einordnungssystemen.

TOP-Zugänglichkeit
zu den Proben, ideal für den regelmäßigen Einsatz

Dem Markt voraus:
Die integrierte BIOSAFE® smart-Steuerung
als Füllstandsregelung und Behälterüberwachung

Videos & images of the BIOSAFE® versions.

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Freezing & storage of
large sample quantities

The Cryocooler BIOSAFE® refrigerator systems 120 to 420 are optimized for maximum capacity with minimized external dimensions to reach temperature below -169°C / -272,2°F / 104,15K. The large, thermodynamically improved, vacuum-insulated lid in an attractive design allows access to stored materials in seconds.

Cryocooler BIOSAFE® systems 500 to 2400 are optimized for maximum capacity with minimized consumption. In the range 500 litres to 2400 litres and more, the containers can be easily loaded via the side-mounted container neck and the smooth-running carousel. The smooth-running castors make BIOSAFE® storage containers mobile and now even more flexible. Cryo cooling at ultra low temperatures is nowadays more important than ever before. Most of the time cryocoolers like our BIOSAFE® use a cryogenic fluid as the working substance. 

The thermodynamic cycle is fed with nitrogen. At room temperature, the liquid nitrogen is typically compressed, precooled in a heat exchanger, and then expanded at a low temperature. The returning low-pressure fluid passes through the heat exchanger to pre-cool the high-pressure fluid before entering the compressor inlet. The cycle is then repeated.

For the cooling of superconducting magnets (cryogenic refrigerators) you should also get in contact with us. We have or we create solutions for any cryo related problems.

designationBIOSAFE® 120BIOSAFE® 220BIOSAFE® 420BIOSAFE® 500BIOSAFE® 800BIOSAFE® 2400
2 ml ampoules in drawers (Ø 12mm)675013000231002626043120120000
2 ml ampoules in cryoboxes (Ø 12mm)7000130002175022750  
5 ml ampoules in drawers (Ø 12mm)337565001155012120  
freezer bag (50ml)* Baxter 4R9951/Miltenyi AND 2ml ampoules (Ø 12mm) in drawers288
-
512
-
832
1500
on request
-
on requeston request
freezer bags (500ml)* Baxter 4R9955/Miltenyi AND 2ml ampoules (Ø 12mm) in drawers144
500
240
1500
480
500
480
-
on requeston request
freezer bags (500ml)* Hempfreeze/Gambro Z2003 AND 2ml ampoules (Ø 12mm) in drawers75
750
150
500
270
500
on request
-
on requeston request

*other bag manufacture and types on request

Benefits:

  • Nitrogen reserve under the adjustable bottom is sufficient for up to two weeks, depending on the size of the tank for cooling even after an occuring failure
  • Redundant hardware for software-independent monitoring of minimum alarm and maximum alarm
  • Low temperatures of -180°C, whether for small or large tanks and whether for wide-neck tanks or tanks with carousel
  • Remote diagnosis and remote monitoring
  • Medcert certified
  • Very low evaporation rate
  • Full storage capacity for gas phase storage
  • Integrated level control device and container monitoring system BIOSAFE® CONTROL ß
  • Stainless steel design
  • Service for commissioning and execution of qualifications (IQ/OQ)

Technical data of the
BIOSAFE® series:

BIOSAFE® - Cryopreservation at its best with our Cryocooler BIOSAFE®
container designationBIOSAFE® 120BIOSAFE® 220BIOSAFE® 420BIOSAFE® 500BIOSAFE® 800BIOSAFE® 2400
vessel materialstainless steelstainless steelstainless steelstainless steelstainless steelstainless steel
content, geometric (l)1512514204909602400
content, geometrically below the adjustable floor (l)21355750117300
weight, empty (kg)1001752253205701300
outer diameter (mm)56071090089010581650
Inside diameter (mm)5146648547959661500
neck diameter (mm)514664854450520830
Total height (mm)1140/10451180/10701190/10701314/10141800/13802100/2100
Adjustment height (mm)625625625800800915
Roll diameter (mm)-80808080100
Evaporation rate, statistical (%/day)2.32.01.51.20.90.6
You can also find all information in our product brochures:

Options

  • Other container sizes
  • Redundant fill level and container monitoring system
  • Connection via Ethernet
  • I/O box with relays
  • Remote monitoring via SMS, e-mail & Co.
  • BIOSAFE® rack systems
BIOSAFE® - Cryopreservation at its best with our Cryocooler BIOSAFE®

Certificates

Certificate
Certificate
Certificate
Certificate

Cryocooler for Cryopreservation: Our BIOSAFE® liquid nitrogen freezer

The BIOSAFE® Cryocooler from Cryotherm has long been a byword for quality and safety. Experience, technology and our know-how make your decision for the cryocooler BIOSAFE® easy. With various sizes and designs of BIOSAFE®, CRYOTHERM offers the complete solution for all cryopreservation tasks.

 

 

Please select a size:

Geometric capacity total [l]